Dose escalation [General Statistics]
Hi Silva,
Nitrox in Porto Santo?
I love this stuff when diving in “special” conditions. Headaches from Vinho Verde Tinto gone in minutes. Beware of the “virtual bottom” by pO2!
OK, makes sense. Haven’t thought of it. Dose escalation studies can’t be done in a crossover.
Yep. Then the PEs will give you the Fabs for each dose level.
PS: Can you send me your mobile No (in case I’ll be arrested for misbehavior in my forthcoming vacation and need help).
❝ @Helmut, my plans were actually to breath some enriched air! Maybe I could become smarter!!
Nitrox in Porto Santo?
I love this stuff when diving in “special” conditions. Headaches from Vinho Verde Tinto gone in minutes. Beware of the “virtual bottom” by pO2!
❝ According to PI, it is a "dose finding" study for a new route of adm. PI pretends to start with the Ref injection dose and then study the other route. All subjects will perform all study treatments (all planned doses), unless safety concerns. It is an exploratory study, not a true bioequivalence study.
OK, makes sense. Haven’t thought of it. Dose escalation studies can’t be done in a crossover.
❝ Facing dosing administration procedure, what would be the ANOVA model: Treatment (dose normalized parameters)+Subject?
Yep. Then the PEs will give you the Fabs for each dose level.
PS: Can you send me your mobile No (in case I’ll be arrested for misbehavior in my forthcoming vacation and need help).
—
Dif-tor heh smusma 🖖🏼 Довге життя Україна!
Helmut Schütz
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Dif-tor heh smusma 🖖🏼 Довге життя Україна!
Helmut Schütz
The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes
Complete thread:
- Using only one sequence Silva 2016-07-28 09:13 [General Statistics]
- Using only one sequence ElMaestro 2016-07-28 09:51
- Paired design Helmut 2016-07-28 11:09
- Paired design Silva 2016-07-28 12:17
- Dose escalationHelmut 2016-07-28 12:47
- Paired design Silva 2016-07-28 12:17
- Paired design Helmut 2016-07-28 11:09
- Using only one sequence DavidManteigas 2016-08-01 11:17
- Using only one sequence ElMaestro 2016-07-28 09:51