Not with such a high CV [Design Issues]
Dear Ohlbe,
Adding to Detlew’s wise words: For a CVwR of 54% I would expect no inflation of the TIE with the FDA’s RSABE and practically none with the EMA’s ABEL.
❝ Any idea about alpha inflation control with such a design ?
Adding to Detlew’s wise words: For a CVwR of 54% I would expect no inflation of the TIE with the FDA’s RSABE and practically none with the EMA’s ABEL.
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Helmut Schütz
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Dif-tor heh smusma 🖖🏼 Довге життя Україна!
![[image]](https://static.bebac.at/pics/Blue_and_yellow_ribbon_UA.png)
Helmut Schütz
![[image]](https://static.bebac.at/img/CC by.png)
The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes
Complete thread:
- Sas proc mixed and 4 period partial replicate Cross over M.tareq 2016-05-03 11:35 [Design Issues]
- What is the purpose? Helmut 2016-05-03 12:43
- What is the purpose? M.tareq 2016-05-03 15:06
- Alpha inflation ? Ohlbe 2016-05-03 15:48
- Alpha inflation d_labes 2016-05-03 16:06
- Not with such a high CVHelmut 2016-05-03 17:49
- High CV? d_labes 2016-05-03 21:07
- Acc. to WHO PQTm Helmut 2016-05-03 21:58
- Sofosbuvir d_labes 2016-05-04 11:50
- Acc. to WHO PQTm Helmut 2016-05-03 21:58
- High CV? d_labes 2016-05-03 21:07
- What is the purpose? Helmut 2016-05-03 12:43