Not with such a high CV [Design Issues]

posted by Helmut Homepage – Vienna, Austria, 2016-05-03 19:49 (3708 d 07:03 ago) – Posting: # 16275
Views: 9,427

Dear Ohlbe,

❝ Any idea about alpha inflation control with such a design ?


Adding to Detlew’s wise words: For a CVwR of 54% I would expect no inflation of the TIE with the FDA’s RSABE and practically none with the EMA’s ABEL.

Dif-tor heh smusma 🖖🏼 Довге життя Україна! [image]
Helmut Schütz
[image]

The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes

Complete thread:

UA Flag
Activity
 Admin contact
23,655 posts in 4,993 threads, 1,570 registered users;
272 visitors (0 registered, 272 guests [including 16 identified bots]).
Forum time: 02:53 CEST (Europe/Vienna)

Most scientists today are devoid of ideas, full of fear, intent on
producing some paltry result so that they can add to the flood
of inane papers that now constitutes “scientific progress”
in many areas.    Paul Feyerabend

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5