Bioequivalence and Bioavailability Forum • What is the purpose?

What is the purpose? [Design Issues]

posted by M.tareq – 2016-05-03 17:06 (3350 d 02:37 ago) – Posting: # 16270
Views: 8,338

Example of the 4 seq
RT2RT1
T1RT2R
T2RT1R
RT1RT2
It was for cost effective as the ref product wasn't avail in the required amount for 2 separate studies

Complete thread:

Sas proc mixed and 4 period partial replicate Cross over M.tareq 2016-05-03 11:35 [Design Issues]
- What is the purpose? Helmut 2016-05-03 12:43
  - What is the purpose?M.tareq 2016-05-03 15:06
  - Alpha inflation ? Ohlbe 2016-05-03 15:48
    - Alpha inflation d_labes 2016-05-03 16:06
    - Not with such a high CV Helmut 2016-05-03 17:49
      - High CV? d_labes 2016-05-03 21:07
        
        Acc. to WHO PQTm Helmut 2016-05-03 21:58
        
        Sofosbuvir d_labes 2016-05-04 11:50