Bioequivalence and Bioavailability Forum • t1/2 prior to Tmax in BE study

t1/2 prior to Tmax in BE study [NCA / SHAM]

posted by Dhruv Shah – India, 2016-03-11 04:48 (2961 d 05:09 ago) – Posting: # 16088
Views: 5,643

In a recent BE study I observed that t1/2 (1 hrs) was faster than Tmax (1.3 hrs). I wanted to know that what does it mean? Moreover if we analyze the data of individual subjects, the occurrence was more in test as compared to reference product. Do we need any special design precautions in such study?

Edit: Category changed. Please follow the Forum’s Policy. [Helmut]

Complete thread:

t1/2 prior to Tmax in BE studyDhruv Shah 2016-03-11 03:48
- t1/2 prior to Tmax in BE study jag009 2016-03-11 20:25
  - t1/2 prior to Tmax in BE study Dhruv Shah 2016-03-16 07:01
- t1/2 prior to Tmax in BE study mittyri 2016-03-11 22:20