t1/2 prior to Tmax in BE study [NCA / SHAM]

posted by Dhruv Shah – India, 2016-03-11 03:48 (1963 d 19:51 ago) – Posting: # 16088
Views: 4,872

In a recent BE study I observed that t1/2 (1 hrs) was faster than Tmax (1.3 hrs). I wanted to know that what does it mean? Moreover if we analyze the data of individual subjects, the occurrence was more in test as compared to reference product. Do we need any special design precautions in such study?


Edit: Category changed. Please follow the Forum’s Policy[Helmut]

Complete thread:

Activity
 Admin contact
21,589 posts in 4,512 threads, 1,530 registered users;
online 4 (0 registered, 4 guests [including 3 identified bots]).
Forum time: Tuesday 00:39 CEST (Europe/Vienna)

The great tragedy of Science – the slaying
of a beautiful hypothesis by an ugly fact.    Thomas Henry Huxley

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5