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Register0.00 concentration value between two measurable concentrations [NCA / SHAM]
Hello Forum Members,
In a data, we received 0.00 concentration value between two measurable concentrations. How to handle this?
Should we exclude the 0.00 concentration value for calculation of AUC?
Also what is the regulatory requirements.
For eg:
Thanks.
Edit: Category changed. Can you please post sampling times instead of the subject number? [Helmut]
In a data, we received 0.00 concentration value between two measurable concentrations. How to handle this?
Should we exclude the 0.00 concentration value for calculation of AUC?
Also what is the regulatory requirements.
For eg:
Subj Conc
1 0.00
1 0.00
1 0.00
1 0.00
1 0.36
1 0.00
1 0.00
1 0.00
1 0.71
1 25.79
1 99.09
1 85.30
1 66.10
1 35.62
1 12.61
1 0.00
1 0.00
1 4.69
1 3.83
1 3.12
1 2.21
1 1.81
1 1.11
1 0.73
1 0.00
1 0.25
1 0.00
1 0.00
1 0.00Thanks.
Edit: Category changed. Can you please post sampling times instead of the subject number? [Helmut]
Complete thread:
- 0.00 concentration value between two measurable concentrationsarl_stat 2016-03-02 10:13
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- 0.00 concentration value between two measurable concentrations arl_stat 2016-03-21 12:41
- “Embedded BQLs” mittyri 2016-03-21 22:17
- “Embedded BQLs” arl_stat 2016-04-15 08:50
- “Embedded BQLs” mittyri 2016-03-21 22:17
- 0.00 concentration value between two measurable concentrations arl_stat 2016-03-21 12:41
Ing. Helmut Schütz