Baseline; another example [Regulatives / Guidelines]

posted by nobody – 2016-02-12 10:10 (2968 d 03:16 ago) – Posting: # 15980
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Dear Mr. Helmut!

Thanks, very nice indeed! Can we start a diploma thesis with adding some more random effects on the baseline (physiology jumps around like hell in practice, due to health status, sports, sleep, food etc.). Would love to see a large set of simulations taking into account all that!

Some 20 years ago I set up some S-plus simulations "retro-NONMEM" with true values and all kinds of variability to study the potential influence of analytical variability on BE decisions. Unfortunately never finished (end of academic time :-D) and lost the files while moving over from one computer to the next in the pre-NAS era...

Kindest regards, nobody

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