Bioequivalence and Bioavailability Forum • please check your dataset file

please check your dataset file [🇷 for BE/BA]

posted by mahmoud-teaima – 2016-02-09 16:00 (2988 d 13:39 ago) – Posting: # 15963
Views: 23,761

Dear YJLee,
thanks for your instructions.
i create the .csv file of my data using macoffice 2011, i did it more than a time.
when i used the ARS method for calculation of Kel, the same error method for subjects 18 and 19 pop up and when i tried to change to the manual selection for calculation of Kel, i got the following error message.

" Point Selection for Lambda_z Estimation
-------------------------------------------------------------------------------
This method is about to select data points for lambda_z estimation based on
the manual selection from each subject's log(conc.) vs. time plot.

1. MS-Windows OS:
Please use your mouse to click the data point on the graph to select
the data points for linear regression. Once you want to stop selection
for each plot, click the 'Stop' menu on the left corner of th plot
and click 'Stop locator.' Alternately, you can use click mouse right-
button to bring up hidden menu and click 'Stop' to stop selection.

2. Linux/Unix (Ubuntu) PC OS:
Use your mouse left (1st)-button to select and mouse right (2nd)-button
to stop selection.

3. Mac OS X:
Use your mouse button to select and hold down the Control key and click
(Control-click) to stop selection.

When finishing the current subject and the next subject's plot will show up.
Do the same procedures until finishing all subjects.

Note: The # of data points should be at least 2's and max. is 6.
Please do NOT choose any data point before Tmax.
...............................................................................

Press Enter to proceed...

****************************************************************************
Data for the Ref. Products:
----------------------------------------------------------------------------
AUC(0-t), AUC(0-inf), AUMC(0-t), AUMC(0-inf), λz, Cl/F, Vd, MRT,
and half-life (T1/2(z))

****************************************************************************

Error in if ("y" %in% log && any(ii <- y <= 0 & !is.na(y))) { :
missing value where TRUE/FALSE needed

Please advise me.

Greetings

—
Mahmoud Teaima, PhD.

Complete thread:

bear v2.7.0 released yjlee168 2015-12-07 09:18 [🇷 for BE/BA]
- Suggestion ElMaestro 2015-12-07 10:12
  - Suggestion yjlee168 2015-12-07 10:55
    - Suggestion Helmut 2015-12-07 14:01
      - Suggestion yjlee168 2015-12-07 18:51
- bear v2.7.0 released Astea 2015-12-10 16:36
  - if Clast is zero in bear yjlee168 2015-12-10 17:23
    - if Clast is zero in bear Astea 2015-12-10 20:50
      - if Clast is zero in bear yjlee168 2015-12-11 03:28
        
        if Clast is zero in bear Astea 2015-12-11 09:39
        
        if Clast is zero in bear yjlee168 2015-12-11 17:16
    - bear v2.7.1 yjlee168 2015-12-15 10:21
      - bear v2.7.1 Astea 2015-12-15 19:32
        
        BLLOQ ≠ 0 with measured drug plasma conc. yjlee168 2015-12-15 20:17
        
        BLLOQ ≠ 0 with measured drug plasma conc. Helmut 2015-12-16 01:45
        
        BLLOQ ≠ 0 with measured drug plasma conc. yjlee168 2015-12-16 11:38
        
        BLLOQ ≠ 0 ∀ t > 0 Helmut 2015-12-16 12:40
        
        BLLOQ ∋ { 0, ≈0, BLLOQ{...} ∀ t > 0} yjlee168 2015-12-16 18:22
        
        BLLOQ at first two time ponts, AUC calculation Astea 2016-01-30 17:11
        
        zero-zero with AUC calculation in bear yjlee168 2016-01-30 19:00
        
        BQL rules in bear mittyri 2016-02-01 22:16
        
        BQL rules in bear yjlee168 2016-02-02 10:59
        possible solutions? yjlee168 2016-02-02 21:30
        zero (0), missing (NA), or BLLOQ (0 or NA) in bear yjlee168 2016-02-03 09:04
        
        zero (0), missing (NA), or BLLOQ (0 or NA) in bear mahmoud-teaima 2016-02-08 21:28
        
        Please avoid Full Quotes (“TOFU”)! Ohlbe 2016-02-09 00:51
        
        error message in bear mahmoud-teaima 2016-02-09 04:55
        
        please check your dataset file yjlee168 2016-02-09 06:40
        
        please check your dataset filemahmoud-teaima 2016-02-09 15:00
        
        please check your dataset file yjlee168 2016-02-09 15:38
        
        A possible R bug? yjlee168 2016-02-09 19:14