Bioequivalence and Bioavailability Forum • maximum sample size at which CV?

maximum sample size at which CV? [🇷 for BE/BA]

posted by nobody – 2016-01-27 10:08 (3342 d 20:24 ago) – Posting: # 15860
Views: 17,540

To me this Fig. tells the story that for GMR < 0.92 frequently the max n is reached BELOW the cut-off of 30% for CV. With a somewhat strange distribution at the very low (not relevant?) end for GMR...

I would like to think about somefink like this FIRST, before enforcing such policies....

—
Kindest regards, nobody

Complete thread:

PowerTOST sample size FDA full replicate T/R ratio at 85% Shuanghe 2016-01-25 17:49 [🇷 for BE/BA]
- PowerTOST sample size FDA full replicate T/R ratio at 85% d_labes 2016-01-26 12:05
  - PowerTOST sample size FDA full replicate T/R ratio at 85% Shuanghe 2016-01-26 12:55
    - PowerTOST sample size FDA full replicate T/R ratio at 85% d_labes 2016-01-26 14:07
    - maximum sample size at which CV? Helmut 2016-01-26 16:31
      - maximum sample size at which CV? nobody 2016-01-26 17:40
      - maximum sample size at which CV? d_labes 2016-01-27 08:41
        
        maximum sample size at which CV?nobody 2016-01-27 09:08
        
        OT: Stop - think -act d_labes 2016-01-27 09:31
      - maximum sample size at which CV? Shuanghe 2016-01-28 12:44
        
        target power 90% Helmut 2016-01-28 13:49
        
        PowerTOST update d_labes 2016-02-01 19:16
        
        #1,000 Helmut 2016-02-01 21:49
        
        OT: post #1,000 d_labes 2016-02-02 21:17
        #1,000 ElMaestro 2016-02-03 16:32
        
        #1,000 Helmut 2016-02-03 16:50
        OT: #1,000 d_labes 2016-02-05 15:50
        
        OT: #1,000 ElMaestro 2016-02-05 17:02
        
        OT: #1,000 d_labes 2016-02-05 19:48
        
        OT: #1,000 ElMaestro 2016-02-06 15:45
        
        OT: #1,000 nobody 2016-02-07 09:50