Bioequivalence and Bioavailability Forum • Partial credit

Partial credit [Design Issues]

posted by ioanam – Romania, 2016-01-22 15:17 (3336 d 14:29 ago) – Posting: # 15845
Views: 11,132

Dear ElMaestro, dear all

since I have the "privilege" to work sometimes with Kinetica, I obtained the new version 5.1 SP1 pack released by Thermo Fisher in 2014, where they fixed the statistical part for the unbalanced studies.

Compared to the previous version, they mention now at the end of analysis:
- ANOVA analysis: Point estimate and confidence interval derived from the least squares estimate (marginal means). - for a balanced study
and for incomplete block analysis: Point estimate and confidence interval derived from the arithmetic means.

Perhaps I am wrong, but calculation based by arithmetic means cannot give bias in such studies?

Wish you a happy weekend.

Ioana

Complete thread:

Montelukast BE study rahul dixit 2011-01-03 15:17 [Design Issues]
- Montelukast BE study bjkim97 2011-01-06 06:45
  - Opinions ... d_labes 2011-01-07 13:51
    - Opinions ... bjkim97 2011-01-11 06:47
  - Montelukast BE study joy_fm 2015-02-05 13:10
    - MHRA’s PARs Helmut 2015-02-05 13:24
      - MHRA’s PARs joy_fm 2015-02-10 17:38
        
        CV from the CI Helmut 2015-02-11 02:05
        
        CI2CV d_labes 2015-02-11 09:16
        
        Beyond the abstract Helmut 2015-02-11 13:01
        
        Beyond the abstract ElMaestro 2015-02-11 13:36
        
        Beyond the abstract & Kinetica Helmut 2015-02-11 14:27
        
        Beyond the abstract & Kinetica d_labes 2015-02-11 14:59
        
        Partial credit ElMaestro 2015-02-11 15:49
        
        Partial creditioanam 2016-01-22 14:17
        
        Partial credit ElMaestro 2016-01-22 14:58
        
        Partial credit Helmut 2016-01-22 15:06