Bioequivalence and Bioavailability Forum • Emax and ED50: NLME

Emax and ED50: NLME [Software]

posted by SDavis – UK, 2015-12-15 12:50 (3847 d 06:30 ago) – Posting: # 15730
Views: 21,586

Dr. Patel,

I suppose it depends a little on what your PD measurement is at the moment, I would say conceptually at least to me, it's easier ot use raw untransformed data, if you have negative values does that mean you are looking at a change from baseline?

Simon

PS to reiterate Helmut's comment that on the Certara forum you could post your project and we can perhaps advise better then.

—
Simon
Senior Scientific Trainer, Certara™
[link=https://www.youtube.com/watch?v=xX-yCO5Rzag[/link]
https://www.certarauniversity.com/dashboard
https://support.certara.com/forums/

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Complete thread:

Emax and ED50: NLME gcpatel126 2015-12-09 18:08 [Software]
- Emax and ED50: NLME Helmut 2015-12-10 02:09
  - Emax and ED50: NLME gcpatel126 2015-12-10 17:34
    - Emax and ED50: NLMESDavis 2015-12-15 11:50
      - Emax and ED50: NLME gcpatel126 2015-12-29 15:49
        
        Emax and ED50: NLME Helmut 2015-12-29 17:46
        
        Emax and ED50: NLME gcpatel126 2015-12-29 18:04
        
        Emax and ED50: NLME Helmut 2015-12-29 19:36
        
        Emax and ED50: NLME gcpatel126 2015-12-30 14:43
        
        Emax and ED50: NLME Helmut 2015-12-30 14:56
        
        Emax and ED50: NLME gcpatel126 2015-12-30 15:19
        
        Validation? Helmut 2015-12-30 16:02
        
        Validation? gcpatel126 2015-12-30 17:47
        
        Validation? Helmut 2015-12-30 21:15
        
        Validation? gcpatel126 2015-12-31 07:06
        
        Validation? gcpatel126 2016-01-11 14:54
        
        EOD Helmut 2016-01-11 22:13