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Register2 way fasting and 3 way fed pilot results analysis [Study Assessment]
Dear Sir
1. For the pilot fasting study based on N=18. The CV in cmax is >30% then we can use 3 way reference replicate scaled with N=36 or we can use two -stage 2x2 with N=50
2. For fed study: The problem in GMR is about 87%. So in this case I recommened to genrate your study using the full replicate scaled with N=36
Dr.Mahmoud Abdel Mohsen
statistician
Amman-Jordan
[email protected]
Edit: Full quote removed. Please delete everything from the text of the original poster which is not necessary in understanding your answer; see also this post! [Ohlbe]
1. For the pilot fasting study based on N=18. The CV in cmax is >30% then we can use 3 way reference replicate scaled with N=36 or we can use two -stage 2x2 with N=50
2. For fed study: The problem in GMR is about 87%. So in this case I recommened to genrate your study using the full replicate scaled with N=36
Dr.Mahmoud Abdel Mohsen
statistician
Amman-Jordan
[email protected]
Edit: Full quote removed. Please delete everything from the text of the original poster which is not necessary in understanding your answer; see also this post! [Ohlbe]
Complete thread:
- 2 way fasting and 3 way fed pilot results analysis unique_one 2015-10-17 09:33 [Study Assessment]
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- 2 way fasting and 3 way fed pilot results analysisMahmoud 2015-11-22 09:51
- Where do these numbers come from? Helmut 2015-11-23 14:01
- Numbers? Helmut 2015-11-23 16:57
- 2 way fasting and 3 way fed pilot results analysisMahmoud 2015-11-22 09:51
Ing. Helmut Schütz