EMA: adjusted α for scABEL (for no-nerds) [RSABE / ABEL]

posted by d_labes  – Berlin, Germany, 2015-11-18 08:25 (2258 d 20:19 ago) – Posting: # 15647
Views: 6,850

(edited by d_labes on 2015-11-18 08:47)

Dear Helmut,

» ...
» R-code at the end for the nerds.

» library(PowerTOST)
» theta0   <- 0.90
» CV       <- c(0.3, 0.5)
» ...
# LL <- min(0.80, exp(-0.76*CV2se(CV[k])))          # EMA's ABEL
# UL <- 1/LL

# for those no-nerds who have forgotten the regulatory constant, the CVswitch 
# and the cap on widening like Helmut :-D (because he doesn't go behind the cap)

limits <- scABEL(CV=CV[k],regulator="EMA")
LL <- limits[1]
UL <- limits[2]
# of course better to replace LL, UL in the code below with limits[1], limits[2]

» ...

BTW: What would you do all your times if PowerTOST wasn't build :lol2:?

Regards,

Detlew

Complete thread:

Activity
 Admin contact
21,844 posts in 4,571 threads, 1,555 registered users;
online 4 (0 registered, 4 guests [including 4 identified bots]).
Forum time: Monday 04:45 CET (Europe/Vienna)

Do, or do not.
There is no ‘try’.    Yoda

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5