PK-Xpress: impressions [Software]
Dear Detlew,
As long as you don’t want to perform the BE-stats it is OK (& if you can stand the strange user-interface). Competitive price.
Leo.
No hands-on experience but last July I endured a two-hours WebEx presentation with the folk in Pune. Observations:
On 31 July I received an e-mail:
They didn’t want to talk about it. Luv told me:
Overall I would say it is an interesting product – which calls for further improvements. For NCA, not that bad. For BE-stats, no way.
❝ Kinetica? I beg you pardon ...
As long as you don’t want to perform the BE-stats it is OK (& if you can stand the strange user-interface). Competitive price.
❝ PK-Xpress seems (beside the spare information given) an "Eierlegende-Wollmilch-Sau".
Leo.
❝ Anybody out there with experiences with that piece of software?
No hands-on experience but last July I endured a two-hours WebEx presentation with the folk in Pune. Observations:
- Open port 80 (HTTP) during installation – pointing to IP 180.87.43.162; “enable the download of executable (.exe) file from web”. That’s a no-go for me.
- Eventually (!) there is a stand-alone installer. They were unsure about it…
- Requires Office 2007+ (Excel’s Solver Add-On). Didn’t manage to find out why. Back luck for people using OpenOffice, LibreOffice, or Office 2000 like myself. IMHO Solver is an undocumented piece of shit.
- Automatic algo for λz (based on max R²adj) may include tmax (like in WinNonlin <v6). However, manual selection of time range possible.
- Only linear trapezoidal method implemented.
- Extrapolation by Clast/λz. Not possible to use Ĉlast/λz.
- No partial AUCs.
- BE-stats. Not for a SASian like you, but might be interesting to others:
- 2×2×2 cross-overs and two-group parallel. Full stop. No higher order crossovers, no replicate designs.
- In crossovers subjects as a random effect (FDA). They were unaware of EMA’s all-fixed effects requirement.
- Given the above, no reference-scaling; working on replicate designs. They were surprised to hear [sic] that the FDA and EMA require different models.
Validation Kit
On 31 July I received an e-mail:
As a part of data refining process, we are working on refining of BE program. As soon as this process is done we will work on the data provided by you and share the desired outputs.
Haven’t heart anything ever since.❝ Expense?
They didn’t want to talk about it. Luv told me:
3,000 USD for each of DissoXpress, IvivcXpress, PK-Xpress. If you are going for whole package the cost would be even lesser. Yearly support charges: 20% of license cost per client.
Much cheaper than Phoenix and slightly below Kinetica.Overall I would say it is an interesting product – which calls for further improvements. For NCA, not that bad. For BE-stats, no way.
—
Dif-tor heh smusma 🖖🏼 Довге життя Україна!![[image]](https://static.bebac.at/pics/Blue_and_yellow_ribbon_UA.png)
Helmut Schütz
![[image]](https://static.bebac.at/img/CC by.png)
The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes
Dif-tor heh smusma 🖖🏼 Довге життя Україна!
![[image]](https://static.bebac.at/pics/Blue_and_yellow_ribbon_UA.png)
Helmut Schütz
![[image]](https://static.bebac.at/img/CC by.png)
The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes
Complete thread:
- Ct curves from single dose to predict multiple dose d_labes 2015-10-08 19:57 [Software]
- Phoenix/WinNonlin: NonParametric Superposition Helmut 2015-10-08 21:02
- Ct curves from single dose to predict multiple dose yjlee168 2015-10-09 06:39
- Software for superposition d_labes 2015-10-09 08:46
- PK-Xpress: impressionsHelmut 2015-10-09 14:23
- PK-Xpress: impressions d_labes 2015-10-09 20:23
- OT: list limbo and (X)HTML Helmut 2015-10-10 01:06
- OT: list limbo and (X)HTML Ohlbe 2015-10-10 23:15
- OT: list limbo and (X)HTML Helmut 2015-10-11 00:01
- OT: list limbo and (X)HTML d_labes 2015-10-11 14:55
- OT: list limbo and (X)HTML Ohlbe 2015-10-10 23:15
- OT: list limbo and (X)HTML Helmut 2015-10-10 01:06
- PK-Xpress: impressions d_labes 2015-10-09 20:23
- PK-Xpress: impressionsHelmut 2015-10-09 14:23
- JGuiB Helmut 2015-10-09 13:16
- Software for superposition d_labes 2015-10-09 08:46