Phoenix/WinNonlin: Non­Para­metric Super­position [Software]

posted by Helmut Homepage – Vienna, Austria, 2015-10-08 23:02 (3411 d 20:46 ago) – Posting: # 15534
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Dear Detlew,

in Phoenix/WinNonlin there is a dedicated tool called “NonParametric Superpostion” which does exactly what you need.
In R (I don’t have any code):IIRC there is a similar tool in Kinetica.
PK-Xpress has such a function as well. In a WebEx-presentation last summer it turned out that only the linear trapezoidal was implemented. Not a good idea to stack in each dosing interval another positive bias on top of the ones before.

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