Pre-dose concentration found higher than preceding sample [Bioanalytics]
Hello Everyone,
I have faced following issue,
I have found concentration in pre-dose sample and that concentration is higher than last sample / time point of Period 01 (i.e. P02, pre-dose concentration is higher than its preceding sample).
In such case we need to repeat the sample (i have repeated sample).
My doubt is,
If i found repeated value different from initial value then what to do? we need to accept which value??? (Initial / Repeated / we need to reported as NR)
eg.
Initial Value - 251 ng / mL
Repeated Value - 0.oo ng / mL (totally different value)
Please give me your suggestions.
Regards,
Mitesh Panchal
I have faced following issue,
I have found concentration in pre-dose sample and that concentration is higher than last sample / time point of Period 01 (i.e. P02, pre-dose concentration is higher than its preceding sample).
In such case we need to repeat the sample (i have repeated sample).
My doubt is,
If i found repeated value different from initial value then what to do? we need to accept which value??? (Initial / Repeated / we need to reported as NR)
eg.
Initial Value - 251 ng / mL
Repeated Value - 0.oo ng / mL (totally different value)
Please give me your suggestions.
Regards,
Mitesh Panchal
Complete thread:
- Pre-dose concentration found higher than preceding sampleMitesh Panchal 2015-08-30 04:54 [Bioanalytics]
- pre-dose concentrations above LLOQ: useful topics mittyri 2015-08-30 19:24
- pre-dose concentrations above LLOQ: useful topics Mitesh Panchal 2015-08-30 20:14
- pre-dose concentrations above LLOQ: useful topics mittyri 2015-08-30 19:24