Partial AUC and missing concentrations [PK / PD]
Dear Hitesh!
That may be an option. But IMHO not the best.
I usually do interpolation in such cases. The same is applied in case of time deviations at 1.5h or at whatever timepoint the partial AUC is needed.
Don't forget the description of your choice how to deal with such cases in your Study protocol!
❝ For AUC0-1.5, if the 1.5hour concentration is missing due to any reason for one product, then do we have to exclude that subject from that product?
That may be an option. But IMHO not the best.
I usually do interpolation in such cases. The same is applied in case of time deviations at 1.5h or at whatever timepoint the partial AUC is needed.
Don't forget the description of your choice how to deal with such cases in your Study protocol!
—
Regards,
Detlew
Regards,
Detlew
Complete thread:
- Partial AUC Hitesh Chauhan 2015-08-19 07:47 [PK / PD]
- Partial AUC and missing concentrationsd_labes 2015-08-19 10:20