ANOVA F-test results and regulators [🇷 for BE/BA]

posted by ElMaestro  – Denmark, 2015-06-12 17:29 (3537 d 02:34 ago) – Posting: # 14951
Views: 14,162

Hmmmm,

❝ We received then and when (not so seldom!) questions about the ANOVA F-test results. Up to the request to comment significant results even for the treatment effects, of no relevance in case of BE studies of course.

❝ Nasty the requests to comment the "validity" of the BE evaluation if period and/or sequence effects are found significant. As they many times come out if Type I tests will be applied, especially for sequence.


Why not just always fit the model with no intercept and type I. The first term is almost guaranteed to have a significant P-value. You can then discuss it as much as you feel like at the nuisance level. Specify Sequence first, and voila here's a nice discussion brewing already :-D You can have a standard answer ready for all procedures.

Pass or fail!
ElMaestro

Complete thread:

UA Flag
Activity
 Admin contact
23,381 posts in 4,914 threads, 1,663 registered users;
63 visitors (0 registered, 63 guests [including 15 identified bots]).
Forum time: 19:03 CET (Europe/Vienna)

Science is built up with facts, as a house is with stones.
But a collection of facts is no more a science
than a heap of stones is a house.    Henri Poincaré

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5