Bioequivalence and Bioavailability Forum • Histogram beast

Histogram beast [Two-Stage / GS Designs]

posted by Helmut – Vienna, Austria, 2015-06-09 17:24 (3574 d 23:12 ago) – Posting: # 14934
Views: 18,963

Dear Detlew!

❝ A better way would be to return the vector of ntot (your suggestion in our correspondence) …

Well, you convinced me that it doesn’t makes sense to return such a large vector (consisting easily of 1 mio elements).

❝ … instead of some histogram-data with standard settings.

Maybe. Maybe not. IMHO, it is good practice to select the number of bins based on the range of data. See help(nclass.Sturges)

❝ That would give you all freedom to design the histogram to your needs.

True.

❝ Example: 100 bins in the histogram

IMHO, that’s a bit over the top. ;-)

I guess that 50 are more than enough to prescind the first stage and show the log-distribution of sample sizes in the second stage. Well, log="x" rightly throws warnings since this is not a histogram proper any more!

[image]

❝ Note the pronounced and outstanding role of N=24, the sample size for stage 1. Not so clear seen in your pictures above for OBF or Zheng. Partly now also seen for HP.

Righty-right! With some tweaks:

[image]

—
Dif-tor heh smusma 🖖🏼 Довге життя Україна!
Helmut Schütz

The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes

Complete thread:

Does unequal alpha distribution make sense? Dr_Dan 2015-05-19 08:29 [Two-Stage / GS Designs]
- Maybe; but watch the TIE! Helmut 2015-05-28 15:04
  - Advantages d_labes 2015-06-05 09:35
    - Advantages ElMaestro 2015-06-05 10:07
      - Advantages – performance measure d_labes 2015-06-05 11:21
        
        Advantages – performance measure Helmut 2015-06-05 13:29
        
        Advantages – performance measure d_labes 2015-06-05 21:27
        
        Advantages – performance measure Helmut 2015-06-05 23:29
        
        Histogram wonder d_labes 2015-06-06 12:58
        
        Histogram charlatanry Helmut 2015-06-09 13:43
        
        Histogram beauty d_labes 2015-06-09 14:55
        
        Histogram beastHelmut 2015-06-09 15:24
- Does unequal alpha distribution make sense? Dr_Dan 2015-05-29 08:33
  - Does unequal alpha distribution make sense? ElMaestro 2015-05-29 09:31
    - Does unequal alpha distribution make sense? nobody 2015-05-29 12:56
      - Old beliefs die hard Helmut 2015-05-29 13:27
        
        Old beliefs die hard nobody 2015-05-29 13:41
        
        Old beliefs die hard Helmut 2015-05-29 18:08
        
        Old beliefs die hard ElMaestro 2015-05-29 18:57
        
        Old beliefs die hard nobody 2015-05-29 20:06
        ♩ ♪♫♬`·.¸¸.·´`·.¸¸. Helmut 2015-06-02 01:52
        
        TSD only an option in exceptional cases Dr_Dan 2015-06-02 08:00
        
        TSD only an option in exceptional cases nobody 2015-06-02 09:23
        
        OT Helmut 2015-06-02 12:07
        
        OT nobody 2015-06-02 12:41
- Banana splits Helmut 2015-06-02 00:48