no para­meters in non­para­me­tric tests… [Nonparametrics]

posted by Helmut Homepage – Vienna, Austria, 2015-05-17 02:33 (3554 d 08:15 ago) – Posting: # 14843
Views: 6,760

Hi Angus,

❝ What we are seeking is a measure of the variability of the Tmax paramater in the test formulation and the variability of the Tmax parameter in the reference formulation.


OK.

❝ In the absence of a distribution.


<nitpick>

In the absence of a distribution defined by mean/variance.
Of course, tmax (in NCA!) follows a – though discrete – distribution.

</nitpick>

❝ One can do a frequency plot and a percentile analysis and simply compare to see if one is less variable than the other…


Given the limited sample size in BE studies a histogram doesn’t tell too much. I would rather go with box plots categorized for treatments. Sometimes easier to interpret – especially if you have more than two treatments.

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