Statistical Comparison Tmax [Nonparametrics]

posted by AngusMcLean – USA, 2015-05-16 19:11 (3238 d 23:41 ago) – Posting: # 14840
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Phoenix WinNonlin 6.4 provides a routine for statistical comparison of Tmax from a 2 way crossover study (Latin Square, 2 periods, 2 sequences) as a non-parametric parameter and confidence intervals are provided. I do not see intrasubject and intersubject variances in the output and I have just made a post to the Pharsight site regarding this.

For bioequivalence of Cmax and AUC pamameters intrasubject and intersubject variance is provided. So I am thinking how to obtain analogous information on Tmax parameter for a two-way cross-over study. I wonder if anyone has done this.

Angus


Edit: Category changed. [Helmut]

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