pooled / total CV [Power / Sample Size]

posted by Helmut Homepage – Vienna, Austria, 2015-05-06 17:40 (3574 d 02:05 ago) – Posting: # 14764
Views: 12,759

Hi John × 2

❝ I want the CV inter-subject to calculate the sample size for a parallel design


Nope. You definitely want the total (aka pooled) one. The fact that you observe the PK-re­sponse only once in a parallel design does not remove the intra-subject variability. Therefore, what you observe consists of both inter- and intra-subject components.

❝ I'm wrong?


Yes. See this post.

Dif-tor heh smusma 🖖🏼 Довге життя Україна! [image]
Helmut Schütz
[image]

The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes

Complete thread:

UA Flag
Activity
 Admin contact
23,381 posts in 4,914 threads, 1,663 registered users;
43 visitors (0 registered, 43 guests [including 9 identified bots]).
Forum time: 18:46 CET (Europe/Vienna)

Science is built up with facts, as a house is with stones.
But a collection of facts is no more a science
than a heap of stones is a house.    Henri Poincaré

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5