Bioequivalence and Bioavailability Forum • Mean means

Mean means [🇷 for BE/BA]

posted by ElMaestro – Denmark, 2015-04-19 11:14 (4076 d 17:24 ago) – Posting: # 14706
Views: 32,929

Hi Helmut,

❝ R T

❝ Method A (EMA, subjects fixed) 7.328141 7.391880

❝ Method B (EMA, subjects random) 7.328141 7.391880

❝ Method C (FDA = mixed efects) 7.328141 7.391880

❝ Marginal means (Gnumeric) 7.328141 7.391880

❝ So why do we get…

❝ bear 7.356274 7.420013

❝ … which are ~3.8% higher for both treatments? No, I’m not satisfied if only the PE agrees – I expect to get a nasty surprise once we start to deal with unbalanced data.

You're right, it does look surprising.
Can you ask Phoenix what the log likelihood was when it had identified the minimum and compare with Yung-jin's logLik above?

And what about those DF's?

—
Pass or fail!
ElMaestro

Thread locked

Complete thread:

Reproducing Bear results in Phoenix mittyri 2015-04-14 08:35 [🇷 for BE/BA]
- Bug in bear? Helmut 2015-04-14 14:07
  - Bug in bear? mittyri 2015-04-14 20:43
    - Bug in bear? Helmut 2015-04-15 02:17
  - use the same dataset? yjlee168 2015-04-20 10:13
- Bugs in bear with replicated demo data set? yjlee168 2015-04-15 09:38
- Bugs fixed in bear? yjlee168 2015-04-17 01:21
  - Bugs fixed in bear? Helmut 2015-04-17 14:25
    - Bugs fixed in bear? yjlee168 2015-04-17 18:50
      - Bugs fixed in bear? ElMaestro 2015-04-17 23:14
        
        lme() in bear yjlee168 2015-04-18 11:12
        
        lme() in bear ElMaestro 2015-04-18 11:28
        
        lme() in bear yjlee168 2015-04-18 12:02
        
        lme() in bear ElMaestro 2015-04-18 13:42
        
        Mean means Helmut 2015-04-18 14:08
        
        Mean means ElMaestro 2015-04-18 16:01
        
        Mean means Helmut 2015-04-19 00:59
        
        Mean meansElMaestro 2015-04-19 09:14
        
        LL and AIC Helmut 2015-04-19 11:08
        
        Confused ElMaestro 2015-04-19 11:42
        
        lsmeans for mixed model in R yjlee168 2015-04-19 23:36
        
        lsmeans() & lme() Helmut 2015-04-20 01:28
        
        lsmeans() & lme() yjlee168 2015-04-20 10:23
        lsmeans() & lme() ElMaestro 2015-04-20 10:35
        
        keep it simple! Helmut 2015-04-20 14:34
        
        keep it simple! ElMaestro 2015-04-20 15:39
        
        ML vs. REML Helmut 2015-04-20 16:35
        
        lme() with NA in R yjlee168 2015-04-19 23:44
      - Dataset Helmut 2015-04-18 13:30
        
        Dataset and lme() in bear yjlee168 2015-04-18 23:14