Bioequivalence and Bioavailability Forum • PK model for 2-group BE study in Phoenix Winnonlin 6.3

PK model for 2-group BE study in Phoenix Winnonlin 6.3 [Software]

posted by scorp2011 – India, 2015-04-01 10:28 (3305 d 09:44 ago) – Posting: # 14648
Views: 5,987

Dear Sir,
Thanks for the prompt response.
I am a bit confused now and I am now trying to be little clear with query.

A crossover BE study conducted in two groups due to logistical reasons.
In group I, 18 subjects were dosed.
In group II, another 18 subjects dosed.
My question is whether there is a provision in Phoenix Winnonlin 6.3 to analyze the group effect. If group effect is found significant, can we calculate bioequivalence parameters after including this group effect in Winnonlin 6.3 after including group effect in fixed variance or any other effects,

Regards
Sonu

Complete thread:

PK model for 2-group BE study in Phoenix Winnonlin 6.3 scorp2011 2015-04-01 06:12 [Software]
- PK model for 2-group BE study in Phoenix Winnonlin 6.3 mittyri 2015-04-01 07:06
  - PK model for 2-group BE study in Phoenix Winnonlin 6.3scorp2011 2015-04-01 08:28
    - PK model for 2-group BE study in Phoenix Winnonlin 6.3 mittyri 2015-04-01 08:48
      - PK model for 2-group BE study in Phoenix Winnonlin 6.3 scorp2011 2015-04-01 09:37
    - BE model for 2-group Xover in Phoenix WinNonlin 6.x Helmut 2015-04-01 13:34