Bioequivalence and Bioavailability Forum

CV from the CI [Design Issues]

posted by Helmut  – Vienna, Austria, 2015-02-11 03:05 (4155 d 04:12 ago) – Posting: # 14399
Views: 16,657

Hi Joy,

❝ I'm sorry, but I still can't find journal which states CV AUCt for Montelukast.

Some people think to be very clever and don’t give the CV in the results. However, the CV can be calculated from the CI and sample size (formulas for 2×2 crossover studies).
Example from the first hit in : C_max 99.7% (89.0–110.4%), n 20 gives CV ~19.8%.

I suggest to get the free statistical software and the package PowerTOST (you will need it sooner or later, believe me)… Once you installed it, try the nice function CVfromCI():

library(PowerTOST)
cat("CV =", round(CVfromCI(lower=0.890, upper=1.104, n=20)*100, 1), "\n")

—
Dif-tor heh smusma 🖖🏼 Довге життя Україна! 
Helmut Schütz


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Complete thread:

• Montelukast BE study rahul dixit 2011-01-03 15:17 [Design Issues] 
  • Montelukast BE study bjkim97 2011-01-06 06:45
    • Opinions ... d_labes 2011-01-07 13:51
      • Opinions ... bjkim97 2011-01-11 06:47
    • Montelukast BE study joy_fm 2015-02-05 13:10
      • MHRA’s PARs Helmut 2015-02-05 13:24
        • MHRA’s PARs joy_fm 2015-02-10 17:38
          • CV from the CIHelmut 2015-02-11 02:05
            • CI2CV d_labes 2015-02-11 09:16
              • Beyond the abstract Helmut 2015-02-11 13:01
                • Beyond the abstract ElMaestro 2015-02-11 13:36
                  • Beyond the abstract & Kinetica Helmut 2015-02-11 14:27
                    • Beyond the abstract & Kinetica d_labes 2015-02-11 14:59
                      • Partial credit ElMaestro 2015-02-11 15:49
                        • Partial credit ioanam 2016-01-22 14:17
                          • Partial credit ElMaestro 2016-01-22 14:58
                            • Partial credit Helmut 2016-01-22 15:06