Bioequivalence and Bioavailability Forum • Truncated 72 hours

Truncated 72 hours [NCA / SHAM]

posted by Dr_Dan – Germany, 2015-02-09 13:59 (3729 d 16:48 ago) – Posting: # 14390
Views: 10,625

Dear MMW
Since the subjects did not show up for the 72 h sample you can not use these subjects for statistical evaluation. As a consequence you have less subjects and wider 90% CI. If the study passes everything is fine, if not you can argue by calculating AUCt for these subjects and all other subjects (AUCt=AUC72) and repeat ANOVA.
I hope this helps.
Kind regards
Dr_Dan

—
Kind regards and have a nice day
Dr_Dan

Complete thread:

Truncated 72 hours mmw 2015-02-09 11:12
- Truncated 72 hoursDr_Dan 2015-02-09 12:59
- Truncated 72 hours Helmut 2015-02-09 16:10
  - Truncated 72 hours nobody 2015-02-09 22:48
    - Truncated 72 hours mmw 2015-02-11 12:57
  - Truncated 72 hours stic-stats 2020-07-13 14:22
    - Truncated 72 hours Helmut 2020-07-13 17:07
      - Truncated 72 hours stic-stats 2020-07-15 06:17
  - Truncated 72 hours M.tareq 2020-07-16 01:36
    - Truncated 72 hours Helmut 2020-07-16 11:56
      - Truncated 72 hours M.tareq 2020-07-16 17:05
        
        PK modeling in BE Helmut 2020-07-16 18:30
        
        PK modeling in BE mittyri 2020-07-19 00:24
        
        PK modeling in BE Helmut 2020-07-19 12:35