## S×F variance [General Statistics]

Dear all – or shall I rather say Angus & John?

Since the other thread (due to indenting of posts) becomes increasingly difficult to read I decided to close it. Please continue here.

Regrettably I had too little spare time to dive into. However, some points:

Since the other thread (due to indenting of posts) becomes increasingly difficult to read I decided to close it. Please continue here.

Regrettably I had too little spare time to dive into. However, some points:

- #14138: John is correct that the setup should essentially follow FDA’s code for
*RSABE*. Therefore, anything obtained from*ABE*is not useful.

- #14141: I developed the RSABE-workflow (see here) in the first place. We presented a poster at the AAPS Meeting in 2013 (download). Ana’s new templates removed the clumsy workaround for joining values of the χ², since
`chiinv(p, df)`

was introduced in PHX/WNL6.4 and can be used in the custom transformation (`RSABE|Prepare Data for RSABE analysis|s2wr and dfd|Step 4`

).

@John: Note that these templates will not work in PHX/WNL6.3.

- #14146: The template is for RSABE, therefore, variability of T is not included (which John correctly pointed out). Yes, it’s doable to add the coding for T.

- #14147: The template covers the partial replicate as well. Still to do for the next version: A setup for the fully replicated two-sequence three-period (TRT|RTR) design which would avoid the convergence issues seen in ABE sometimes. BTW, I’ll submit a protocol with such a design to FDA’s OGD next month for review.

- #14149: Modifying the ABE-part doesn’t do the job (see #1 above). What you could do: Copy the entire
`Prepare Data for RSABE analysis`

workflow and change the coding in the second one from R to T. Don’t forget to change all filters and transformations. Then you have*both*the results for R and T. Proceed from there.

—

Helmut Schütz

The quality of responses received is directly proportional to the quality of the question asked. 🚮

Science Quotes

*Dif-tor heh smusma*🖖Helmut Schütz

The quality of responses received is directly proportional to the quality of the question asked. 🚮

Science Quotes

### Complete thread:

- S×F varianceHelmut 2014-12-23 15:32 [General Statistics]
- S×F variance AngusMcLean 2014-12-23 16:32
- S×F variance Helmut 2014-12-23 17:17
- S×F variance AngusMcLean 2014-12-28 23:12

- S×F variance Helmut 2014-12-23 17:17
- S×F variance AngusMcLean 2014-12-23 20:56
- S×F variance jag009 2014-12-23 23:07
- S×F variance AngusMcLean 2014-12-24 01:39
- S×F variance jag009 2014-12-24 16:21
- S×F variance AngusMcLean 2014-12-24 17:50

- S×F variance jag009 2014-12-24 16:21
- S×F variance AngusMcLean 2015-01-06 17:30
- S×F variance: Followup jag009 2015-01-08 22:42
- S×F variance: Followup AngusMcLean 2015-01-09 01:44
- S×F variance: Followup jag009 2015-01-12 16:53
- S×F variance: Followup AngusMcLean 2015-01-12 20:56
- S×F variance: 3rd opinion Helmut 2015-01-13 01:25
- S×F variance: 3rd opinion AngusMcLean 2015-01-13 20:13
- S×F variance: 3rd opinion AngusMcLean 2015-01-14 21:29
- S×F variance: 3rd opinion AngusMcLean 2015-01-29 23:38

- S×F variance: 3rd opinion Helmut 2015-01-13 01:25
- S×F variance: Followup AngusMcLean 2015-01-30 23:24
- S×F variance: Followup jag009 2015-02-02 16:31
- S×F variance: Followup AngusMcLean 2015-02-02 17:22
- S×F variance: Followup jag009 2015-02-05 18:14
- S×F variance: Followup AngusMcLean 2015-02-06 01:39

- S×F variance: Followup jag009 2015-02-06 17:13
- S×F variance: Followup AngusMcLean 2015-02-06 19:36
- S×F variance: Followup jag009 2015-02-17 22:49
- S×F variance: Followup AngusMcLean 2015-02-19 23:25
- S×F variance: Followup jag009 2015-02-21 21:08
- S×F variance: Followup AngusMcLean 2015-02-22 17:25
- S×F variance: Followup jag009 2015-02-23 16:58

- S×F variance: Followup AngusMcLean 2015-02-22 17:25

- S×F variance: Followup jag009 2015-02-21 21:08

- S×F variance: Followup AngusMcLean 2015-02-19 23:25

- S×F variance: Followup jag009 2015-02-17 22:49

- S×F variance: Followup AngusMcLean 2015-02-06 19:36

- S×F variance: Followup jag009 2015-02-05 18:14

- S×F variance: Followup AngusMcLean 2015-02-02 17:22

- S×F variance: Followup jag009 2015-02-02 16:31

- S×F variance: Followup AngusMcLean 2015-01-12 20:56

- S×F variance: Followup jag009 2015-01-12 16:53

- S×F variance: Followup AngusMcLean 2015-01-09 01:44

- S×F variance: Followup jag009 2015-01-08 22:42

- S×F variance AngusMcLean 2014-12-24 01:39
- S×F variance AngusMcLean 2015-01-06 18:48
- S×F variance jag009 2015-01-07 21:28
- S×F variance Helmut 2015-01-08 16:10
- S×F variance: Typo. jag009 2015-01-08 17:32
- S×F variance AngusMcLean 2015-01-08 18:51
- S×F variance jag009 2015-01-08 20:02
- S×F variance AngusMcLean 2015-01-08 20:27
- S×F variance jag009 2015-01-08 20:33

- S×F variance AngusMcLean 2015-01-08 20:27

- S×F variance jag009 2015-01-08 20:02

- S×F variance AngusMcLean 2015-01-08 18:51

- S×F variance: Typo. jag009 2015-01-08 17:32

- S×F variance Helmut 2015-01-08 16:10

- S×F variance jag009 2015-01-07 21:28

- S×F variance AngusMcLean 2014-12-23 16:32