Difference between Cminss and Ctauss? [NCA / SHAM]
Please help me with the definitions of Ctau and Cmin at steady state.
According to EMEA BE guideline for MR products: Ctauss is Concentration at the end of the dosing interval at steady state
and
Cminss: Minimum plasma concentration at steady state.
Please explain me in details the difference. And why the values of Ctauss are higher than Cminss?
At which point in the Steady state P'kinetics graph do we measure both of them?
Edit: Category changed. [Helmut]
According to EMEA BE guideline for MR products: Ctauss is Concentration at the end of the dosing interval at steady state
and
Cminss: Minimum plasma concentration at steady state.
Please explain me in details the difference. And why the values of Ctauss are higher than Cminss?
At which point in the Steady state P'kinetics graph do we measure both of them?
Edit: Category changed. [Helmut]
Complete thread:
- Difference between Cminss and Ctauss?tekwani.sunil 2014-12-03 07:10
- Difference between Cminss and Ctauss? Helmut 2014-12-03 13:11
- Difference between Cminss and Ctauss? tekwani.sunil 2014-12-04 05:53
- Difference between Cminss and Ctauss? Helmut 2014-12-04 14:21
- Difference between Cminss and Ctauss? tekwani.sunil 2014-12-04 05:53
- Difference between Cminss and Ctauss? Helmut 2014-12-03 13:11