Bioequivalence and Bioavailability Forum • Some comments

Some comments [Software]

posted by ElMaestro – Denmark, 2014-10-09 13:52 (3863 d 05:03 ago) – Posting: # 13676
Views: 39,957

Hi yung-jin,
Hi all,

a few comments so far:

Just read the documentation for the Proc Mixed settings; looks to me like it isn't possible at all to control starter values for the optimiser? That would be rather silly, if you ask me.
Anyways, if it is possible to select starter values then I'd propose to first fit the stuff with ML (sometimes-to-often has much better convergence) and then feed the fit values onto the REML optimiser as starter values.
If someone can show me how to pass values by reference (~pointer) in R then I think I might be able to write R code for this stuff. Not good/solid/clever/smart/fast code at all, but code that does the job. Could take a bit of time, though.

To explain what I mean by passing values by reference consider this example:

Bar=function(X)

{

   X=X+1

   cat("Hello Mom!\n")

   return(0)

}





Foo=function(B)

{

   Bar(B)  

   cat("B is",B,"\n")

}  

Foo(7)

- it will print 7 and not 8, as long as the function parameter is passed by value and not by reference.

I simply need a way for the argument to be passed by reference so that Bar can change it and Foo can continue doing stuff on B once the change has happened.

Plenty websites will discuss how to do it. But I am just ElMaestro and my brain is walnut-sized so I need more than a link to a website to understand it, please.

—
Pass or fail!
ElMaestro

Complete thread:

reference dataset elba.romero 2013-07-02 05:08 [Software]
- Public datasets Helmut 2013-07-02 15:44
  - Public datasets yjlee168 2013-07-03 03:10
    - Public datasets elba.romero 2013-07-03 05:19
      - Public datasets yjlee168 2013-07-03 13:11
        
        Challenging data sets Helmut 2013-07-03 16:32
        
        Fantastic idea? ⇒ Challenging data sets yjlee168 2013-07-04 08:06
        
        Fantastic idea! Helmut 2013-07-04 13:18
    - NIST; cross-validation Helmut 2013-07-03 14:28
      - NIST; cross-validation yjlee168 2013-07-03 23:47
        
        NIST; cross-validation Helmut 2013-07-04 00:45
  - Public datasets elba.romero 2013-07-03 05:10
- Eight Reference Datasets (2×2×2 ☑) Helmut 2014-10-06 02:24
  - What??? ElMaestro 2014-10-06 13:20
    - What??? Helmut 2014-10-06 17:08
      - What??? ElMaestro 2014-10-06 17:31
        
        What the heck‽ Helmut 2014-10-06 19:05
  - link of electronic supplement material? yjlee168 2014-10-07 09:53
    - link of electronic supplement material? nobody 2014-10-07 10:59
      - Thanks! yjlee168 2014-10-07 11:35
        
        Thanks! nobody 2014-10-07 11:44
        
        Direct links & hint Helmut 2014-10-07 13:54
    - Replicated designs are relevant, too ElMaestro 2014-10-07 12:36
      - Replicated designs are relevant, too yjlee168 2014-10-07 13:00
        
        RSABE: SAS and PHX/WNL only? Helmut 2014-10-07 14:47
        
        for the future? yjlee168 2014-10-08 10:05
        
        Star Trek: The Next Generation Helmut 2014-10-09 00:26
        
        Star Trek: The Next Generation d_labes 2014-10-09 08:09
        Star Trek: The Next Generation nobody 2014-10-09 08:23
        Star Trek: The Next Generation yjlee168 2014-10-09 11:06
        
        Some commentsElMaestro 2014-10-09 11:52
        
        Some comments yjlee168 2014-10-09 12:18
        
        Proc MIXED - start value d_labes 2014-10-10 08:35
        
        Proc MIXED - start value ElMaestro 2014-10-10 11:44
        Proc MIXED - start value yjlee168 2014-10-11 21:09
        
        Proc MIXED - start value ElMaestro 2014-10-11 21:18
        
        Optimizer settings Helmut 2014-10-09 14:08
        
        Optimizer settings nobody 2014-10-09 15:32
        Optimizer settings yjlee168 2014-10-09 18:14
        
        FDA’s model… Helmut 2014-10-09 18:34
  - Just received a letter… Helmut 2014-11-03 14:54
  - 11 Reference Datasets (2-group parallel ☑) Helmut 2014-12-09 15:51