## LSM limbo [General Sta­tis­tics]

Dear Helmut,

» Manually? Never done that.

» It’s a complete mess. Subjects with incomplete data are excluded from the estimation of σ²WR, but kept in the calculation of the upper 95% boundary (FDA) or excluded for the calculation of the 90% CI (EMA, all fixed effects. A mixed-effects model is not acceptable for EMA).

I would not think for even a split second of trying to recalculate manually the 90 % CI or σ²WR... But I was hoping there would be a simple way to at least recalculate LSMs (or to understand how they are calculated).

Thanks anyway !

Regards
Ohlbe