Multiple Outliers using Lund’s Procedure [Outliers]

posted by Pankaj Bhangale – India, 2014-07-10 16:23 (3366 d 06:18 ago) – Posting: # 13255
Views: 5,581

Dear All,

We encountered a situation wherein the data shows only one outlier subject by Lund's procedure in 2X2 crossover design study. After removing this outlier subject, when the data is again run for Lund’s test, another outlier subject is observed.

Can we perform Lund’s test in such repetative manner to remove outliers from the data?

Is it acceptable by usfda regulatory subject to redosing study with multiple outlier subjects with control subjects)?

Please Guide me.
Really appreciate for any help.

Best Regards,
Pankaj Bhangale

Complete thread:

UA Flag
 Admin contact
22,761 posts in 4,775 threads, 1,628 registered users;
16 visitors (0 registered, 16 guests [including 9 identified bots]).
Forum time: 22:41 CEST (Europe/Vienna)

Medical researches can be divided into two sorts:
those who think that meta is better and those
who believe that pooling is fooling.    Stephen Senn

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz