Bioequivalence and Bioavailability Forum

SAS PROC GLM with group effect [General Statistics]

posted by ElMaestro – Denmark, 2014-05-23 14:31 (4048 d 11:41 ago) – Posting: # 12993
Views: 15,751

Hi Silva,

❝ From all the discussions about group effect within the forum, a thought came to me? Do we really need to test Group effect? If not tested, what happens is the increase of MS error and therefore CI's are expected to be widenned, which increases Producer's risk! Does FDA or EMA really ask for group effect?

With Group being a between-subjects factor I am not sure group in itself affects any within-variability. Although I think the formulation x group interaction would steal a df and would be tested against the model residual (within). You are right that any step towards increasing the model residual translates into producer's risk.
I need to look closer at the model matrix constructs to be sure, though.

—
Pass or fail!
ElMaestro

Complete thread:

SAS PROC GLM with group effect Silva 2014-05-19 10:57 [General Statistics]
- SAS PROC GLM with group effect ElMaestro 2014-05-19 11:51
  - SAS PROC GLM with group effect Silva 2014-05-22 12:01
    - SAS PROC GLM with group effect d_labes 2014-05-22 14:11
      - SAS PROC GLM with group effect Silva 2014-05-22 16:54
- SAS PROC GLM with group effect d_labes 2014-05-19 13:02
- SAS PROC GLM with group effect Silva 2014-05-23 12:12
  - SAS PROC GLM with group effectElMaestro 2014-05-23 12:31
  - Acceptability of software Helmut 2014-05-23 12:47
    - Acceptability of software Lucas 2014-11-14 12:21
      - Acceptability of software Helmut 2014-11-14 14:11

SAS PROC GLM with group effect [General Sta­tis­tics]

Complete thread:

SAS PROC GLM with group effect [General Statistics]