A fixed dose combination dissolution evaluation [Dissolution / BCS / IVIVC]

posted by mahonny – India, 2014-04-14 17:22 (3450 d 07:50 ago) – Posting: # 12836
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@luvblooms

Thanks for your comments.

❝ a. Was there any heap formation at 50 rpm? The difference between 50 and 75 rpm points towards.


Heap is formed, that is right. But currently we have only reference tablets for BE study, therefore, we dont want to change the DT method :s

❝ b. Why not trying basket apparatus and check?


Basket method was tried as well, however heap still remains


Edit: Standard quotes restored. [Helmut]

Mahonny

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