Bioequivalence and Bioavailability Forum • A fixed dose combination dissolution evaluation

A fixed dose combination dissolution evaluation [Dissolution / BCS / IVIVC]

posted by mahonny – India, 2014-04-14 17:22 (4022 d 07:00 ago) – Posting: # 12836
Views: 10,475

@luvblooms

Thanks for your comments.

❝ a. Was there any heap formation at 50 rpm? The difference between 50 and 75 rpm points towards.

Heap is formed, that is right. But currently we have only reference tablets for BE study, therefore, we dont want to change the DT method :s

❝ b. Why not trying basket apparatus and check?

Basket method was tried as well, however heap still remains

Edit: Standard quotes restored. [Helmut]

—
Mahonny

Complete thread:

A fixed dose combination dissolution evaluation mahonny 2014-04-04 09:00 [Dissolution / BCS / IVIVC]
- discriminatory methods? Dr_Dan 2014-04-04 10:43
  - discriminatory methods? mahonny 2014-04-04 11:12
    - discriminatory methods? Dr_Dan 2014-04-04 12:43
- A fixed dose combination dissolution evaluation mahonny 2014-04-04 13:29
  - A fixed dose combination dissolution evaluation luvblooms 2014-04-07 08:28
    - A fixed dose combination dissolution evaluationmahonny 2014-04-14 15:22
- A fixed dose combination dissolution evaluation susan dong 2018-11-26 08:35
  - A fixed dose combination dissolution evaluation snow2020 2018-12-05 06:27

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