Bioequivalence and Bioavailability Forum 12:37 CET

Main page Policy/Terms of Use Abbreviations Latest Posts

 Log in |  Register |  Search

Qualitative analysis of the ANOVA residuals [General Sta­tis­tics]

posted by Helmut Homepage - Vienna, Austria, 2014-02-19 15:22  - Posting: # 12450
Views: 9,523

Hi Lucas,

» We've been asked to perform a qualitative analysis of the residuals of the ANOVA.

ANVISA?

» Now, I don't know what that analysis is supposed to acomplish, so I don't know what is supposed to be done.

IMHO, assessing the studentized residuals makes sense. See also Canada’s Guidance, Section 2.3.4.
  1. From the model’s raw residuals calculate the standardized residuals (aka internally studentized residuals).
  2. From them calculate the studentized residual (aka deleted studentized residual, extrenally studentized residual).
Both are directly accessible in SAS and R – and with a little bit of struggle – in Phoenix/WinNonlin. I would suggest to come up with a box-plot (optionally overlayed with jittered values) and ±3 as an optical reference. Looks like this:

[image]

Cheers,
Helmut Schütz
[image]

The quality of responses received is directly proportional to the quality of the question asked. ☼
Science Quotes

Complete thread:

Activity
 Mix view
Bioequivalence and Bioavailability Forum |  Admin contact
18,881 posts in 4,026 threads, 1,271 registered users;
online 27 (1 registered, 26 guests [including 20 identified bots]).

Being ignorant is not so much a shame,
as being unwilling to learn.    Benjamin Franklin

The BIOEQUIVALENCE / BIOAVAILABILITY FORUM is hosted by
BEBAC Ing. Helmut Schütz
HTML5 RSS Feed