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RegisterPassing SD and Failing MD [General Statistics]
Hi HS
We have done a couple of studies for a molecule (BCS class II molecule, solubility lesser at higher pH, almost insoluble at pH 6 and above, MR pellets) .
In SD we got results like this
Cmax: 97% (87- 108)
AUC: 89 (82-96)
In MD, product failed in Cmin ss and AUCTss.
Exact values I do not remember, I need to look my old book for the same.
If you need details let me know, I will look for the same.
Regards
We have done a couple of studies for a molecule (BCS class II molecule, solubility lesser at higher pH, almost insoluble at pH 6 and above, MR pellets) .
In SD we got results like this
Cmax: 97% (87- 108)
AUC: 89 (82-96)
In MD, product failed in Cmin ss and AUCTss.
Exact values I do not remember, I need to look my old book for the same.
If you need details let me know, I will look for the same.
Regards
—
~A happy Soul~
~A happy Soul~
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Ing. Helmut Schütz