Bioequivalence and Bioavailability Forum

Conc at dosing interval [General Statistics]

posted by jag009 – NJ, 2013-11-25 18:48 (4224 d 03:58 ago) – Posting: # 11964
Views: 14,955

Hi Helmut,

I sometime use the following too:
Compare the concentration at 24 hours (or the dosing interval for the product) between the test and reference. Yes for BE the difference in general is not huge but it can affect the MD BE outcome with respect to Cmax.

John

Complete thread:

Simulation of data to predict Steady state cakhatri 2013-11-24 10:13 [General Statistics]
- Nonparametric superposition Helmut 2013-11-24 14:30
  - Nonparametric superposition jag009 2013-11-24 23:13
    - Nonlinear nightmare Helmut 2013-11-25 02:56
      - Nonlinear nightmare jag009 2013-11-25 17:43
        
        Nonlinear nightmare Helmut 2013-11-26 14:32
        
        Nonlinear nightmare jag009 2013-11-26 16:00
        
        OT: Vienna Helmut 2013-11-26 16:27
        
        OT: Vienna jag009 2013-11-26 17:29
        
        OT: Vienna Helmut 2013-11-27 13:04
  - Conc at dosing intervaljag009 2013-11-25 17:48
    - Conc at dosing interval Helmut 2013-11-26 15:01
      - Conc at dosing interval jag009 2013-11-26 17:31
        
        Conc at dosing interval Helmut 2013-11-27 13:10
        
        Conc at dosing interval jag009 2013-11-27 20:00
        Passing SD and Failing MD luvblooms 2013-11-28 09:19
        
        Passing SD and Failing MD Helmut 2013-11-29 17:29
        
        Passing SD and Failing MD luvblooms 2013-11-29 18:57
        
        Cτ predictive of Cmin Helmut 2013-11-30 17:25

Conc at dosing interval [General Sta­tis­tics]

Complete thread:

Conc at dosing interval [General Statistics]