IVIVC calculations [Dissolution / BCS / IVIVC]

posted by mahendra – US, 2013-10-24 16:10  – Posting: # 11753
Views: 22,104

I am working in analytical method development for Pharmaceutical company.

I want to just learn how to do IVIVC comparison.

For a Batch of drug product:

for Invitro: data: % drug dissolved in 15 min, 30 min, 45 min intervals.
For invivo: What data do i need ? Like AUC, Cmax etc.

I am unbale to see examples on this. Colud any one help me to learn this? Its my interest.

I have Minitab 16: is it capble to IVIVC?

I see recently in a post that mentioned IVIVC is possible in R software? I dont know about R software and i have not used it? Is it simple to run IVIVC in R to learn?

I want to see practically how IVIVC data give the information for next development?

Thanks in advance

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