Bioequivalence and Bioavailability Forum • sampling time points for truncated AUC

sampling time points for truncated AUC [Regulatives / Guidelines]

posted by Helmut – Vienna, Austria, 2007-09-25 15:33 (6476 d 13:22 ago) – Posting: # 1133
Views: 5,473

Dear Nirali!

❝ what will be appropriate truncated sampling time points, if half life of

❝ drug is around 70 hrs?

You may use the algorithm presented in this post.
I would set the first sampling time point t(1) to the expected t_max and
the last sampling time point t(n) to 72 hours.

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Dif-tor heh smusma 🖖🏼 Довге життя Україна!
Helmut Schütz

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Complete thread:

ANVISA: 90% CI for AUCINF in 72hrs truncated BE Study Nirali 2007-09-21 06:26 [Regulatives / Guidelines]
- ANVISA: truncated AUC Helmut 2007-09-21 13:26
  - ANVISA: truncated AUC Nirali 2007-09-22 17:53
  - sampling time points for truncated AUC Nirali 2007-09-25 07:29
    - sampling time points for truncated AUCHelmut 2007-09-25 13:33
      - sampling time points for truncated AUC Purav 2007-09-27 06:35
        
        sampling time points for truncated AUC Ohlbe 2007-09-27 10:25