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RegisterLocation parameters [General Statistics]
posted by Helmut 
– Vienna, Austria, 2013-08-08 15:10 (4274 d 10:09 ago) – Posting: # 11250
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Hi ElMaestro,
what’s the distribution of concentrations (or derived metrics like AUC)? AUC seems to be log-normal (see here). I dunno whether anybody explored concentrations. If we don’t believe in exotic matter (e.g., negative mass) truncation at zero (or LLOQ?) makes sense. Or is the distribution log-normal? Probably (will pool some data time allowing). Note that in PopPK an error model with censored data is often used.
what’s the distribution of concentrations (or derived metrics like AUC)? AUC seems to be log-normal (see here). I dunno whether anybody explored concentrations. If we don’t believe in exotic matter (e.g., negative mass) truncation at zero (or LLOQ?) makes sense. Or is the distribution log-normal? Probably (will pool some data time allowing). Note that in PopPK an error model with censored data is often used.
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Helmut Schütz
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Dif-tor heh smusma 🖖🏼 Довге життя Україна!
Helmut Schütz
The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes
Complete thread:
- Geometric mean of normal dist etc. ElMaestro 2013-08-07 13:18 [General Statistics]
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- Geometric mean of normal dist etc. Helmut 2013-08-07 16:20
- Geometric mean of normal dist etc. ElMaestro 2013-08-07 16:28
- Overheated brain Helmut 2013-08-07 16:37
- Location parametersHelmut 2013-08-08 13:10
- Location parameters ElMaestro 2013-08-08 13:52
- Distribution of concentrations Helmut 2013-08-08 14:35
- Location parameters ElMaestro 2013-08-08 13:52
- Geometric mean of normal dist etc. ElMaestro 2013-08-07 16:28
- Geometric mean of normal dist etc. Helmut 2013-08-07 16:20
Ing. Helmut Schütz