Improbable [Software]
❝ […] if you are an egg-head with an IQ of 6 billion and qualified for a professorship at MIT…
At least chances for the former are somewhat low:
pnorm(6e9, mean=100, sd=15, lower.tail=FALSE)
❝ Science is really making progress these days.
Yep.
❝ Pharsight are you reading this? (Come on Simon, we know you are!)

BTW, to quote Senn and Grieve*
(2) Why would an investigator plan a trial with the object of proving equality of two formulations if the variances were believed different?
(4) Welch’s test is not universally accepted as being a valid approach to the problem of statistical inference for differences in means in the presence of heteroscedasticity.
- Senn S, Grieve AP. A Comment on Optimal Allocations for Bioequivalence Studies. Biometrics. 1999;55(4):1314–5.doi 10.1111/j.0006-341X.1999.01314.x
Dif-tor heh smusma 🖖🏼 Довге життя Україна!
![[image]](https://static.bebac.at/pics/Blue_and_yellow_ribbon_UA.png)
Helmut Schütz
![[image]](https://static.bebac.at/img/CC by.png)
The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes
Complete thread:
- Parallel design [unequal variances] in Phoenix/WinNonlin Helmut 2013-07-04 20:22 [Software]
- Parallel design [unequal variances] in Phoenix/WinNonlin ElMaestro 2013-07-04 21:16
- Workaround Helmut 2013-07-04 22:13
- 3-trt study? ElMaestro 2013-07-04 22:37
- ؟ῳ ♠♣♥♦♪♫ѳ٭ Helmut 2013-07-04 23:08
- 3-trt study? ElMaestro 2013-07-04 22:37
- Satterthwaite’s df in Phoenix/WinNonlin Helmut 2013-07-05 15:13
- Satterthwaite’s df in Phoenix/WinNonlin ElMaestro 2013-07-05 17:08
- Wikipedia, the free encyclopedia that anyone can edit. Helmut 2013-07-05 17:15
- Wikipedia, the free encyclopedia that anyone can edit. ElMaestro 2013-07-05 18:25
- ImprobableHelmut 2013-07-05 18:40
- Wikipedia, the free encyclopedia that anyone can edit. ElMaestro 2013-07-05 18:25
- Wikipedia, the free encyclopedia that anyone can edit. Helmut 2013-07-05 17:15
- Satterthwaite’s df in Phoenix/WinNonlin ElMaestro 2013-07-05 17:08
- Workaround Helmut 2013-07-04 22:13
- Parallel design [unequal variances] in Phoenix/WinNonlin ElMaestro 2013-07-04 21:16