Bioequivalence and Bioavailability Forum • NIST; cross-validation

NIST; cross-validation [Software]

posted by Helmut – Vienna, Austria, 2013-07-03 16:28 (4326 d 03:14 ago) – Posting: # 10929
Views: 42,084

Dear Yung-jin,

❝ So there is no "reference dataset" at all. Is that possible that we can have some kind of "reference datasets" like NIST StRD Nonlinear Regression Datasets or similar?

If Elba will succeed in convincing NIST of its importance we will have one… ;-)

Note that NIST’s datasets do not necessarily represent the “truth”, only the “best-available” solutions. Quote from the background information:

The generated datasets are designed to challenge specific computations. Real-world data include challenging datasets such as the Thurber problem, and more benign datasets such as Misra1a. The certified values are "best-available" solutions, obtained using 128-bit precision and confirmed by at least two different algorithms and software packages using analytic derivatives.

❝ Otherwise, in order to validate bear, users will need to pay for commercial computer programs.

Why? If you compare bear’s results with the published ones you don’t have to have the software which generated them.

P.S.: Yung-jin added the validation to bear’s website (162 pages, 4.45 MB). Now it’s up to the user to compare the different programs’ output. BTW: WinNonlin Pro 4.01, but which versions of bear and SAS?

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Helmut Schütz

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Complete thread:

reference dataset elba.romero 2013-07-02 05:08 [Software]
- Public datasets Helmut 2013-07-02 15:44
  - Public datasets yjlee168 2013-07-03 03:10
    - Public datasets elba.romero 2013-07-03 05:19
      - Public datasets yjlee168 2013-07-03 13:11
        
        Challenging data sets Helmut 2013-07-03 16:32
        
        Fantastic idea? ⇒ Challenging data sets yjlee168 2013-07-04 08:06
        
        Fantastic idea! Helmut 2013-07-04 13:18
    - NIST; cross-validationHelmut 2013-07-03 14:28
      - NIST; cross-validation yjlee168 2013-07-03 23:47
        
        NIST; cross-validation Helmut 2013-07-04 00:45
  - Public datasets elba.romero 2013-07-03 05:10
- Eight Reference Datasets (2×2×2 ☑) Helmut 2014-10-06 02:24
  - What??? ElMaestro 2014-10-06 13:20
    - What??? Helmut 2014-10-06 17:08
      - What??? ElMaestro 2014-10-06 17:31
        
        What the heck‽ Helmut 2014-10-06 19:05
  - link of electronic supplement material? yjlee168 2014-10-07 09:53
    - link of electronic supplement material? nobody 2014-10-07 10:59
      - Thanks! yjlee168 2014-10-07 11:35
        
        Thanks! nobody 2014-10-07 11:44
        
        Direct links & hint Helmut 2014-10-07 13:54
    - Replicated designs are relevant, too ElMaestro 2014-10-07 12:36
      - Replicated designs are relevant, too yjlee168 2014-10-07 13:00
        
        RSABE: SAS and PHX/WNL only? Helmut 2014-10-07 14:47
        
        for the future? yjlee168 2014-10-08 10:05
        
        Star Trek: The Next Generation Helmut 2014-10-09 00:26
        
        Star Trek: The Next Generation d_labes 2014-10-09 08:09
        Star Trek: The Next Generation nobody 2014-10-09 08:23
        Star Trek: The Next Generation yjlee168 2014-10-09 11:06
        
        Some comments ElMaestro 2014-10-09 11:52
        
        Some comments yjlee168 2014-10-09 12:18
        
        Proc MIXED - start value d_labes 2014-10-10 08:35
        
        Proc MIXED - start value ElMaestro 2014-10-10 11:44
        Proc MIXED - start value yjlee168 2014-10-11 21:09
        
        Proc MIXED - start value ElMaestro 2014-10-11 21:18
        
        Optimizer settings Helmut 2014-10-09 14:08
        
        Optimizer settings nobody 2014-10-09 15:32
        Optimizer settings yjlee168 2014-10-09 18:14
        
        FDA’s model… Helmut 2014-10-09 18:34
  - Just received a letter… Helmut 2014-11-03 14:54
  - 11 Reference Datasets (2-group parallel ☑) Helmut 2014-12-09 15:51