Bioequivalence and Bioavailability Forum

Calculate what? [NCA / SHAM]

posted by Helmut  – Vienna, Austria, 2013-06-03 20:11 (4398 d 01:19 ago) – Posting: # 10718
Views: 19,961

Hi Ken!

❝ May I know which software in R you refer to that can be used to calculate the data ?

… to calculate what? For imputation use my code above (simply give the time­points in the t-vector and concentrations in C). For the lin-up/log-down trape­zoidal rule in the calculation of AUC see the end of my code in this post.
I guess it’s easier to wait for the next version of bear.*

---

See there for the new version.

—
Dif-tor heh smusma 🖖🏼 Довге життя Україна! 
Helmut Schütz


The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes

Complete thread:

• handling of missing data gracehung 2013-05-20 07:35 [NCA / SHAM] 
  • Lin-up/log-down trapezoidal avoids most trouble Helmut 2013-05-20 14:22
    • Lin-up/log-down trapezoidal avoids most trouble yjlee168 2013-05-22 08:25
      • Multiple peaks: fallback to linear trapezoidal Helmut 2013-05-22 20:25
        • Multiple peaks: fallback to linear trapezoidal yjlee168 2013-05-22 21:57
          • No interpolation Helmut 2013-05-22 23:25
            • No interpolation yjlee168 2013-05-23 11:43
              • Spaghetti & other pasta Helmut 2013-05-23 15:15
                • Spaghetti & other pasta yjlee168 2013-05-23 20:47
                  • Spaghetti & other pasta Helmut 2013-05-23 21:29
                    • Spaghetti & other pasta yjlee168 2013-05-23 22:46
                      • Spaghetti & other pasta Helmut 2013-05-24 01:24
                        • Spaghetti & other pasta yjlee168 2013-05-24 09:17
            • No interpolation Ken Peh 2013-05-30 19:55
              • Different algos! Helmut 2013-05-30 22:38
                • Different algos! Ken Peh 2013-06-03 17:52
                  • Calculate what?Helmut 2013-06-03 18:11
      • Lin-up/log-down trapezoidal example Helmut 2013-05-25 15:09
        • Lin-up/log-down trapezoidal example yjlee168 2013-05-25 19:45
  • handling of missing data Ohlbe 2013-05-20 21:45
    • Sorry Helmut 2013-05-21 13:53
      • Sorry gracehung 2013-05-23 01:06
        • Uncertain time point Helmut 2013-05-23 01:35