Bioequivalence and Bioavailability Forum

IVIVC / Mapping [Dissolution / BCS / IVIVC]

posted by Helmut  – Vienna, Austria, 2007-09-01 16:49 (6074 d 09:08 ago) – Posting: # 1046
Views: 36,811

Dear HMY!

❝ Anyone know how to calculate the plasma profile using in vitro dissolution profile and IVIVC?

Yes.

❝ i.e. in vivo absorption profile -> plasma profile

This is the concept of ‘Mapping’. You should have all tools given previously in this thread handy.
Once you have an IVIVC established, it’s trivial to calculate in vivo dissolution and therefore predict the plasma profile.
What is your question?

—
Dif-tor heh smusma 🖖🏼 Довге життя Україна! 
Helmut Schütz


The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes

Complete thread:

• IVIVC Studies MGR 2007-02-02 10:10 [Dissolution / BCS / IVIVC] 
  • IVIVC Studies Helmut 2007-02-07 19:56
    • IVIVC Studies venu 2007-02-23 06:58
      • IVIVC Studies Dipesh Jayswal 2007-03-16 07:53
        • Wagner-Nelson, Loo-Riegelman Helmut 2007-03-16 15:39
          • Wagner-Nelson, Loo-Riegelman Dipesh Jayswal 2007-03-19 10:04
          • Deconvolution drcampos 2007-03-19 15:26
            • Numerical Deconvolution Helmut 2007-03-19 16:20
              • Numerical Deconvolution drcampos 2007-03-19 21:17
              • Numerical Deconvolution Rayhope 2021-10-07 14:25
                • Daniel still active in the Forum? Helmut 2021-10-07 16:38
                  • Daniel still active in the Forum? Rayhope 2021-10-08 09:07
                    • Daniel still active in the Forum? Rayhope 2021-11-11 08:35
          • Wagner-Nelson Dipesh Jayswal 2007-03-21 08:21
            • Wagner-Nelson Helmut 2007-03-21 12:13
              • IVIVC jesse08 2007-09-01 01:38
                • IVIVC / MappingHelmut 2007-09-01 14:49
                  • IVIVC / Mapping jesse08 2007-09-02 00:32
                    • IVIVC / Software Helmut 2007-09-02 12:03
                      • IVIVC / Software jesse08 2007-10-03 02:13
                        • IVIVC / Software Nirali 2007-11-21 12:38
                          • at least 3 formulations for IVIVC Helmut 2007-11-21 15:25
                            • at least 3 formulations for IVIVC Nirali 2007-11-22 07:53
                              • at least 1 formulation for Level A Helmut 2007-11-22 09:53
                                • at least 1 formulation for Level A Nirali 2007-11-27 06:05
                          • IVIVC / Software SDavis 2009-09-25 09:11
            • IVIVC set up/ requirements sonu 2009-09-23 08:47