IVIVC / Mapping [Dissolution / BCS / IVIVC]

posted by Helmut Homepage – Vienna, Austria, 2007-09-01 16:49 (5867 d 13:24 ago) – Posting: # 1046
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Dear HMY!

❝ Anyone know how to calculate the plasma profile using in vitro dissolution profile and IVIVC?

Yes. :cool:

❝ i.e. in vivo absorption profile -> plasma profile

This is the concept of ‘Mapping’. You should have all tools given previously in this thread handy.
Once you have an IVIVC established, it’s trivial to calculate in vivo dissolution and therefore predict the plasma profile.
What is your question?

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