Bioequivalence and Bioavailability Forum • VarCov typo

VarCov typo [Design Issues]

posted by d_labes – Berlin, Germany, 2013-04-08 18:50 (4816 d 02:05 ago) – Posting: # 10372
Views: 7,573

Dear Old pirate!

❝ This, I think, does not look right; e.g. lower left and upper right should be identical;

Got me!

I correct as follows:

       T            R            R

T  s2bT + s2wT  rho*sbT*sbR  rho*sbT*sbR

R  rho*sbT*sbR  s2bR + s2wR     s2bR

R  rho*sbT*sbR    s2bR       s2bR + s2wR

❝ The zeros elsewhere applies whenever two observations are from different subjects.

Agree. This is the assumption of independence of data from different subjects.

—
Regards,

Detlew

Complete thread:

Highly variable drugs of different dosage forms Ken Peh 2013-04-05 14:00 [Design Issues]
- Highly variable drugs of different dosage forms jag009 2013-04-05 15:46
  - Highly variable drugs of different dosage forms Ken Peh 2013-04-05 20:26
- Two tests, one ref, replicate for ref for possiblescaling. ElMaestro 2013-04-05 17:37
  - Two tests, one ref, replicate for ref for possiblescaling. Ken Peh 2013-04-05 20:23
    - Hush hush ElMaestro 2013-04-06 00:28
      - Hush hush baby d_labes 2013-04-08 11:57
        
        Hush hush baby ElMaestro 2013-04-08 12:23
        
        VarCov typod_labes 2013-04-08 16:50
    - T1-T2-R-R d_labes 2013-04-08 09:10