Bioequivalence and Bioavailability Forum • Highly variable drugs of different dosage forms

Highly variable drugs of different dosage forms [Design Issues]

posted by jag009 – NJ, 2013-04-05 17:46 (4819 d 22:44 ago) – Posting: # 10355
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Hi ken.

❝ For highly variable drug, we need to carry out replicate design, either partial or full replicate. How to fit one reference product and one test product in different dosage forms into replicate design ? Any idea ? :confused:

You mean setting up the study treatment sequences for T1=capsules, T2=Tablet, Reference (replicate)?

John

Complete thread:

Highly variable drugs of different dosage forms Ken Peh 2013-04-05 14:00 [Design Issues]
- Highly variable drugs of different dosage formsjag009 2013-04-05 15:46
  - Highly variable drugs of different dosage forms Ken Peh 2013-04-05 20:26
- Two tests, one ref, replicate for ref for possiblescaling. ElMaestro 2013-04-05 17:37
  - Two tests, one ref, replicate for ref for possiblescaling. Ken Peh 2013-04-05 20:23
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