Bioequivalence and Bioavailability Forum • iteratively adjusted alpha

iteratively adjusted alpha [RSABE / ABEL]

posted by martin – Austria, 2013-03-26 17:19 (4048 d 04:17 ago) – Posting: # 10287
Views: 20,033

dear helmut!

iteratively adjusted alpha – super idea!

you may find of interest that two weirdos published a paper about iterative alpha adjustment a few years ago (paper) soley based on simulation results (not enough skilled to provide evidence via mathematical proof).

best regards

martin

Complete thread:

‘alpha’ of scaled ABE? d_labes 2013-03-15 15:56 [RSABE / ABEL]
- ‘alpha’ of scaled ABE? Helmut 2013-03-15 17:27
  - ’alpha’ of scaled ABE: design d_labes 2013-03-16 20:10
    - N=24, 48 d_labes 2013-03-18 08:11
      - adaptive design without adjustment martin 2013-03-25 20:47
        
        α adjustment? Helmut 2013-03-26 15:21
        
        iteratively adjusted alphamartin 2013-03-26 16:19
        
        throw away our sample size tables? Helmut 2013-03-26 18:02
        
        if real martin 2013-03-26 19:44
        
        regulators don’t care? Helmut 2013-03-26 21:18
        
        adjusting α Helmut 2013-08-11 16:19
        
        target α in sim’s? Helmut 2013-03-27 15:38
        
        target α in sim’s? martin 2013-03-27 16:36
        
        If it is real: results Helmut 2013-03-28 23:20
        
        having alpha martin 2013-03-28 15:08
        
        fixed swr Helmut 2013-03-28 23:34
        
        fixed swr martin 2013-03-29 15:07
        
        Yes but no but yes but no but… Helmut 2013-03-29 16:10