Bioequivalence and Bioavailability Forum • Two groups (e.g. logistics)

Two groups (e.g. logistics) [Design Issues]

posted by arl_stat – India, 2013-03-26 10:42 (4472 d 03:40 ago) – Posting: # 10284
Views: 9,076

Dear HS,

❝ since I recently had to deal with deficiency letters from the Gulf States (Saudia Arabia, Emirates), I would suggest the following procedure:

   Fixed:  Sequence + Treatment + Period + Group + Treatment × Group

   Random: Subject(Sequence)

Tests for Group and Treatment × Group.

❝

❝ If the ‘Treatment × Group Interaction’ term is statistically not significant (p>0.05), the simple model (i.e., naïve pooling of data without both Group-terms) can be applied.

In additional to above model, Is it necessary to add factor Period(group). If yes then what it would imply. This is For a 2 way crossover study where subject has been divided into two equal groups with equal washout period.

Complete thread:

Statistical Analysis Plan sangeeta 2007-06-25 16:04 [Design Issues]
- Statistical Analysis Plan M.Vasu 2007-07-02 08:29
  - Two groups (e.g. logistics) Helmut 2007-07-03 19:18
    - Two groups (e.g. logistics) M.Vasu 2007-07-05 08:40
    - Two groups (e.g. logistics) sangeeta 2007-07-21 12:05
      - Two groups (e.g. logistics) Helmut 2007-11-16 15:07
        
        Two groups (e.g. logistics) MGR 2007-11-26 06:55
        
        Two groups (e.g. logistics) Helmut 2007-11-26 11:49
        
        Two groups (e.g. logistics)arl_stat 2013-03-26 09:42
- Statistical Analysis Plan MGR 2007-07-02 13:27