adaptive design without adjustment [RSABE / ABEL]
dear all!
this behavior may be due to an adaptive choice of a statistical method in face of the data without any "adjustment" for this adaptation. this reminds me on the "flowchart" approach many CROs are using which should be avoided.
best regards
martin
PS.: no idea at the moment how to account for this.
PPS.: why flowcharts should not be used link.
this behavior may be due to an adaptive choice of a statistical method in face of the data without any "adjustment" for this adaptation. this reminds me on the "flowchart" approach many CROs are using which should be avoided.
best regards
martin
PS.: no idea at the moment how to account for this.
PPS.: why flowcharts should not be used link.
Complete thread:
- ‘alpha’ of scaled ABE? d_labes 2013-03-15 15:56 [RSABE / ABEL]
- ‘alpha’ of scaled ABE? Helmut 2013-03-15 17:27
- ’alpha’ of scaled ABE: design d_labes 2013-03-16 20:10
- N=24, 48 d_labes 2013-03-18 08:11
- adaptive design without adjustmentmartin 2013-03-25 20:47
- α adjustment? Helmut 2013-03-26 15:21
- iteratively adjusted alpha martin 2013-03-26 16:19
- throw away our sample size tables? Helmut 2013-03-26 18:02
- if real martin 2013-03-26 19:44
- regulators don’t care? Helmut 2013-03-26 21:18
- adjusting α Helmut 2013-08-11 16:19
- if real martin 2013-03-26 19:44
- target α in sim’s? Helmut 2013-03-27 15:38
- target α in sim’s? martin 2013-03-27 16:36
- If it is real: results Helmut 2013-03-28 23:20
- having alpha martin 2013-03-28 15:08
- fixed swr Helmut 2013-03-28 23:34
- fixed swr martin 2013-03-29 15:07
- Yes but no but yes but no but… Helmut 2013-03-29 16:10
- fixed swr martin 2013-03-29 15:07
- fixed swr Helmut 2013-03-28 23:34
- target α in sim’s? martin 2013-03-27 16:36
- throw away our sample size tables? Helmut 2013-03-26 18:02
- iteratively adjusted alpha martin 2013-03-26 16:19
- α adjustment? Helmut 2013-03-26 15:21
- adaptive design without adjustmentmartin 2013-03-25 20:47
- N=24, 48 d_labes 2013-03-18 08:11
- ’alpha’ of scaled ABE: design d_labes 2013-03-16 20:10
- ‘alpha’ of scaled ABE? Helmut 2013-03-15 17:27