Bioequivalence and Bioavailability Forum

PK Vs Analytical [Bioanalytics]

posted by Charl – 2007-07-23 12:44 (6503 d 12:23 ago) – Posting: # 924
Views: 14,027

Hi

what is the best way to decide on the LLOQ depending on pharmacokinetics point of view, rather than depending on the analytical parameters to decide?

Is there a proper way to estimate the linearity range from PK data rather than analytical approach?

My point can we work on the analytical method development depending on the PK and statistical output to design our analytical method?

Complete thread:

• PK Vs AnalyticalCharl 2007-07-23 10:44 [Bioanalytics] 
  • PK Vs Analytical Helmut 2007-07-23 18:04
    • PK Vs Analytical Charl 2007-07-24 10:31
      • PK Vs Analytical Helmut 2007-07-24 13:42
        • PK Vs Analytical Charl 2007-07-24 15:02
  • PK Vs Analytical drshiv 2007-07-31 08:47
    • PK Vs Analytical Charl 2007-07-31 14:07
      • PK Vs Analytical drshiv 2007-08-07 16:37
        • NCA 'model independent'? Helmut 2007-08-11 20:09
          • NCA 'model independent'? drshiv 2007-08-12 13:08
            • Numerical integration Helmut 2007-08-12 18:51
              • Numerical integration drshiv 2007-08-14 08:29